Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

Romain Guièze (1) , Vivian Liu , Daniel Rosebrock , Alexis Jourdain , María Hernández-Sánchez , Aina Martinez Zurita , Jing Sun , Elisa ten Hacken , Kaitlyn Baranowski , Philip Thompson , Jin-Mi Heo , Zachary Cartun , Ozan Aygün , J. Bryan Iorgulescu , Wandi Zhang , Giulia Notarangelo , Dimitri Livitz , Shuqiang Li , Matthew Davids , Anat Biran , Stacey Fernandes , Jennifer Brown , Ana Lako , Zoe Ciantra , Matthew Lawlor , Derin Keskin , Namrata Udeshi , William Wierda , Kenneth Livak , Anthony A Letai , Donna Neuberg , J. Wade Harper , Steven Carr , Federica Piccioni , Christopher Ott , Ignaty Leshchiner , Cory Johannessen , John Doench , Vamsi Mootha , Gad Getz , Catherine Wu

1 CHELTER - Role of intra-Clonal Heterogeneity and Leukemic environment in ThErapy Resistance of chronic leukemias

Domaines: Hématologie

Romain Guièze, Vivian Liu, Daniel Rosebrock, Alexis Jourdain, María Hernández-Sánchez, et al.. Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies. Cancer Cell, 2019, 36 (4), pp.369-384.e13. ⟨10.1016/j.ccell.2019.08.005⟩. ⟨hal-02318784⟩