Skip to Main content Skip to Navigation
New interface
Conference papers

Physics-based Deep Neural Network for Real-Time Lesion Tracking in Ultrasound-guided Breast Biopsy

Abstract : In the context of ultrasound (US) guided breast biopsy, image fusion techniques can be employed to track the position of US-invisible lesions previously identified on a pre-operative image. Such methods have to account for the large anatomical deformations resulting from probe pressure during US scanning within the real-time constraint. Although biomechanical models based on the finite element (FE) method represent the preferred approach to model breast behavior, they cannot achieve real-time performances. In this paper we propose to use deep neural networks to learn large deformations occurring in ultrasound-guided breast biopsy and then to provide accurate prediction of lesion displacement in real-time. We train a U-Net architecture on a relatively small amount of synthetic data generated in an offline phase from FE simulations of probe-induced deformations on the breast anatomy of interest. Overall, both training data generation and network training are performed in less than 5 hours, which is clinically acceptable considering that the biopsy can be performed at most the day after the pre-operative scan. The method is tested both on synthetic and on real data acquired on a realistic breast phantom. Results show that our method correctly learns the deformable behavior modelled via FE simulations and is able to generalize to real data, achieving a target registration error comparable to that of FE models, while being about a hundred times faster.
Complete list of metadata

Cited literature [24 references]  Display  Hide  Download
Contributor : Andrea Mendizabal Connect in order to contact the contributor
Submitted on : Tuesday, October 29, 2019 - 10:13:49 AM
Last modification on : Monday, March 21, 2022 - 5:22:04 PM
Long-term archiving on: : Thursday, January 30, 2020 - 12:11:16 PM


Files produced by the author(s)


  • HAL Id : hal-02311277, version 1



Andrea Mendizabal, Eleonora Tagliabue, Jean-Nicolas Brunet, Diego Dall'Alba, Paolo Fiorini, et al.. Physics-based Deep Neural Network for Real-Time Lesion Tracking in Ultrasound-guided Breast Biopsy. Computational Biomechanics for Medicine XIV, Oct 2019, Shenzhen, China. ⟨hal-02311277⟩



Record views


Files downloads