Natural Abundance Deuterium NMR Spectroscopy

Abstract : Compared to 1H nuclear magnetic resonance (NMR), natural abundance deuterium (NAD) NMR spectroscopy benefits from specific advantages. In particular, NAD NMR spectra provide key information on molecular orientation and dynamics and are not obscured by homonuclear couplings. The use of 2H NMR is often limited by its low gyromagnetic ratio and its low natural isotopic abundance (Vienna standard mean ocean water = 0.0155%). Nevertheless, thanks to the instrumental and methodological developments, NAD NMR is nowadays possible for a large number of samples, including isotropic liquids, liquid crystals, and solids. We review here the major applications of NAD NMR and notably the isotope fractionation and stereochemical analysis using chiral orienting media.
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Contributor : Philippe Lesot <>
Submitted on : Tuesday, October 8, 2019 - 5:41:08 PM
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Philippe Lesot, Olivier Lafon. Natural Abundance Deuterium NMR Spectroscopy. Encyclopedia of Spectroscopy and Spectrometry, Elsevier, pp.1-14, 2016, ⟨10.1016/B978-0-12-409547-2.12110-9⟩. ⟨hal-02308860⟩



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