Halonium-Induced Polyene Cyclizations

Agathe D’hollander , Laure Peilleron , Tatyana Grayfer (1) , Kevin Cariou (1)

1 ICSN - Institut de Chimie des Substances Naturelles

This review covers the methods that chemists have developed to access halogenated polycyclic structures from polyenes, by emulating Nature's enzymatic machineries. From pioneering studies to the most recent developments, the different strategies, whether based on the use of standard reagents or on the design of specific ones, will be presented. Finally, asymmetric reactions and applications for the total synthesis of natural products will be exposed.

Domaines: Chimie; Chimie organique

Agathe D’hollander, Laure Peilleron, Tatyana Grayfer, Kevin Cariou. Halonium-Induced Polyene Cyclizations. Synthesis: Journal of Synthetic Organic Chemistry, 2019, 51 (08), pp.1753-1769. ⟨10.1055/s-0037-1612254⟩. ⟨hal-02307164⟩