Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy

Eloise Thomas (1) , Jyothi Menon (1) , Joshua Owen (1) , Irini Skaripa-Koukelli (1) , Sheena Wallington (1) , Michael Gray (1) , Christophoros Mannaris (1) , Veerle Kersemans (1) , Danny Allen (1) , Paul Kinchesh (1) , Sean Smart (1) , Robert Carlisle (1) , Katherine Vallis (1)

1 University of Oxford

Mots clés: Cancer; Liposome.; Enhanced Delivery; Radionuclide Therapy; Chemotherapy; Ultrasound; Radiopharmaceutical; Indium-111; Functionalisation

Domaines: Ingénierie biomédicale; Sciences du Vivant [q-bio]; Biotechnologies; Cancer; Autre; Imagerie; Médecine nucléaire; Radiochimie

Eloise Thomas, Jyothi Menon, Joshua Owen, Irini Skaripa-Koukelli, Sheena Wallington, et al.. Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy. Theranostics, 2019, 9 (19), pp.5595-5609. ⟨10.7150/thno.34669⟩. ⟨hal-02287691⟩