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Article Dans Une Revue Graefe's Archive for Clinical and Experimental Ophthalmology Année : 2015

Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy

Isabelle Audo
  • Fonction : Auteur
Kiyoko Gocho
  • Fonction : Auteur
Florence Rossant
  • Fonction : Auteur
Saddek Mohand-Said
  • Fonction : Auteur
Kevin Loquin
  • Fonction : Auteur
  • PersonId : 1216677
J. Sahel
  • Fonction : Auteur
M. Pâques
  • Fonction : Auteur

Résumé

Background: To report functional and high-resolution retinal imaging abnormalities, including adaptive optics (AO) throughout the course of acute macular neuroretinopathy (AMNR).

Methods: Two female patients (four eyes) with a diagnosis of AMNR were observed at the Clinical Investigation Center, CHNO des Quinze-Vingts, Paris, France. The patients underwent detailed ophthalmic examination including best-corrected visual acuity, slit-lamp examination, kinetic and static perimetry, full-field and multifocal electroretinogram, infrared reflectance, autofluorescence imaging and spectral-domain optical coherence tomography (SD-OCT) and AO fundus imaging at presentation and during follow-up.

Results: Both cases showed concomitant loss of integrity of the outer retinal structures on SD-OCT, and marked abnormalities on AO imaging with disruption of the visibility of the cone mosaic. In the first case, photoreceptor damage was seen to progress during several weeks before healing. In both cases, there were persistent morphological abnormalities of photoreceptors 1 year after onset.

Conclusion: This study further highlights the value of AO fundus imaging to facilitate detection, mapping, and monitoring of damage to the cone outer segments during AMNR. In particular, residual damage to the cone mosaic can be precisely documented.

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Dates et versions

hal-02287203 , version 1 (13-09-2019)

Identifiants

  • HAL Id : hal-02287203 , version 1

Citer

Isabelle Audo, Kiyoko Gocho, Florence Rossant, Saddek Mohand-Said, Kevin Loquin, et al.. Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy. Graefe's Archive for Clinical and Experimental Ophthalmology, 2015, pp.1-10. ⟨hal-02287203⟩
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