Assessment of adeno-associated virus gene therapies efficacy on acid alpha-glucosidase restoration and glycogen storage correction in cardiac muscle of Pompe disease mice using synchrotron infrared and ultraviolet microspectroscopies

Laurence Dubreil (1) , Lydie Lagalice (1) , Johan Deniaud (1) , Antoine Sabourin , Claire Lovo (1) , Karim Bey (1) , Juliette Hordeaux (1) , Chantal Thorin (2) , Christophe Sandt (3) , Frédéric Jamme (3) , Marie-Anne Colle (1)

1 PAnTher - Physiopathologie Animale et bioThérapie du muscle et du système nerveux
2 Laboratoire de Physiopathologie Animale et Pharmacologie Fonctionnelle
3 SSOLEIL - Synchrotron SOLEIL

Assessment of adeno-associated virus gene therapies efficacy on acid alpha-glucosidase restoration and glycogen storage correction in cardiac muscle of Pompe disease mice using synchrotron infrared and ultraviolet microspectroscopies

Domaines: Sciences du Vivant [q-bio]

Laurence Dubreil, Lydie Lagalice, Johan Deniaud, Antoine Sabourin, Claire Lovo, et al.. Assessment of adeno-associated virus gene therapies efficacy on acid alpha-glucosidase restoration and glycogen storage correction in cardiac muscle of Pompe disease mice using synchrotron infrared and ultraviolet microspectroscopies. Journal of Spectral Imaging, 2019, ⟨10.1255/jsi.2019.a13⟩. ⟨hal-02278997⟩