Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond, Antiviral Res, vol.155, pp.76-88, 2018. ,
Clinical implications of antiviral resistance in influenza, Viruses, vol.7, pp.4929-4973, 2015. ,
Host-directed therapies for bacterial and viral infections, Nat Rev Drug Discov, vol.17, pp.35-56, 2018. ,
A CRISPR toolbox to study virus-host interactions, Nat Rev Microbiol, vol.15, pp.351-64, 2017. ,
Combating intracellular pathogens with repurposed host-targeted drugs, ACS Infect Dis, vol.4, pp.88-92, 2018. ,
Prevention and treatment of respiratory viral infections: presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference, Antiviral Res, vol.149, pp.118-160, 2018. ,
Regulation of translation initiation in eukaryotes: mechanisms and biological targets, Cell, vol.136, pp.731-776, 2009. ,
The unfolded protein response: from stress pathway to homeostatic regulation, Science, vol.334, pp.1081-1087, 2011. ,
Lipid-dependent regulation of the unfolded protein response, Curr Opin Cell Biol, vol.33, pp.67-73, 2015. ,
Heme-regulated eIF2? kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency, EMBO J, vol.20, pp.6909-6927, 2001. ,
Signal integration in the endoplasmic reticulum unfolded protein response, Nat Rev Mol Cell Biol, vol.8, pp.519-548, 2007. ,
Activation of the antiviral kinase PKR and viral countermeasures, Viruses, vol.1, pp.523-567, 2009. ,
Translational resistance of late alphavirus mRNA to eIF2? phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR, Genes Dev, vol.20, pp.87-100, 2006. ,
Protein kinase R is responsible for the phosphorylation of eIF2? in rotavirus infection, J Virol, vol.84, pp.10457-66, 2010. ,
Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2 GTP met-tRNAiMet ternary complex availability, MBoC, vol.17, pp.4632-4676, 2006. ,
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2?, J Cell Biol, vol.153, pp.1011-1033, 2001. ,
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells, J Cell Biol, vol.163, pp.767-75, 2003. ,
Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit, Science, vol.348, pp.239-281, 2015. ,
PPP1R15A-mediated dephosphorylation of eIF2? is unaffected by Sephin1 or Guanabenz, Elife, vol.6, p.26109, 2017. ,
A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2?, J Biol Chem, vol.293, pp.7766-76, 2018. ,
Decoding the selectivity of eIF2? holophosphatases and PPP1R15A inhibitors, Nat Struct Mol Biol, vol.24, pp.708-724, 2017. ,
Translational control is required for the unfolded protein response and in vivo glucose homeostasis, Mol Cell, vol.7, pp.1165-76, 2001. ,
Mutations in a translation initiation factor identify target of a memory-enhancing compound, Science, vol.348, pp.1027-1057, 2015. ,
Visualizing the replication of respiratory syncytial virus in cells and in living mice, Nat Commun, vol.5, p.5104, 2014. ,
Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature, PLoS Pathog, vol.14, 2018. ,
Enterovirus 68 is associated with respiratory illness and shares biological features with both the enteroviruses and the rhinoviruses, J Gen Virol, vol.85, pp.2577-84, 2004. ,
In vivo labelling of adenovirus DNA identifies chromatin anchoring and biphasic genome replication, J Virol, 2018. ,
Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses, Mol Cell Proteomics, vol.10, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00639495
High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses, J Vis Exp, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01113538
, Frontiers in Immunology | www.frontiersin.org, vol.10, p.134, 2019.
A Virulence factor of myxoma virus colocalizes with NF-?B in the nucleus and interferes with inflammation, J Virol, vol.78, pp.2510-2516, 2004. ,
Real-time visualization and quantification of human Cytomegalovirus replication in living cells using the ANCHOR DNA labeling technology, J Virol, vol.92, pp.571-589, 2018. ,
Nucleolar localization of influenza A NS1: striking differences between mammalian and avian cells, Virol J, vol.7, p.63, 2010. ,
Deletion of the C-terminal ESEV domain of NS1 does not affect the replication of a low-pathogenic avian influenza virus H7N1 in ducks and chickens, J Gen Virol, vol.94, pp.50-58, 2013. ,
Japanese encephalitis circulation pattern in swine of northern Vietnam and consequences for swine's vaccination recommendations, Transbound Emerg Dis, vol.65, pp.1485-92, 2018. ,
TaqMan reverse transcription polymerase chain reaction for the detection of Japanese encephalitis virus, J Vet Sci, vol.5, pp.345-51, 2004. ,
Species specificity of type III interferon activity and development of a sensitive luciferase-based bioassay for quantitation of mouse IFN-?, J Interferon Cytokine Res, vol.38, pp.469-79 ,
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response, Nat Cell Biol, vol.2, pp.326-358, 2000. ,
Species-specific contribution of the four C-terminal amino acids of influenza A virus NS1 protein to virulence, J Virol, vol.84, pp.6733-6780, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-01222877
, Rev Off Int Epizoot, vol.34, pp.549-56, 2015.
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure, J Biol Chem, vol.280, pp.16925-16958, 2005. ,
West nile virus-induced interferon production is mediated by the double-stranded RNA-dependent protein kinase PKR, J Virol, vol.81, pp.11148-58, 2007. ,
Respiratory syncytial virus: current and emerging treatment options, Clinicoecon Outcomes Res, vol.6, pp.217-242, 2014. ,
Measles and measles vaccination: a review, JAMA Pediatr, vol.170, pp.1209-1224, 2016. ,
Global emergence of enterovirus D68: a systematic review, Lancet Infect Dis, vol.16, 2016. ,
Influenza virus non-structural protein NS1: interferon antagonism and beyond, J Gen Virol, vol.95, pp.2594-611, 2014. ,
Influenza A virus virulence depends on two amino acids in the N-terminal domain of its NS1 protein to facilitate inhibition of the RNA-dependent protein kinase PKR, J Virol, vol.91, pp.198-215, 2017. ,
Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR, J Biol Chem, vol.274, pp.5953-62, 1999. ,
A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis, Virology, vol.363, pp.236-279, 2007. ,
Blocking double-stranded RNA-activated protein kinase PKR by Japanese encephalitis virus nonstructural protein 2A, J Virol, vol.86, pp.10347-58, 2012. ,
Induction of GADD34 is necessary for dsRNA-dependent interferon-? production and participates in the control of Chikungunya virus infection, PLoS Pathog, vol.8, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00964879
Structural and functional analysis of the GADD34:PP1 eIF2? phosphatase, Cell Rep, vol.11, pp.1885-91, 2015. ,
Stress-induced gene expression requires programmed recovery from translational repression, EMBO J, vol.22, pp.1180-1187, 2003. ,
Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase, ERp57. Sci Rep, vol.8, p.10425, 2018. ,
Mechanisms of antiviral activity of iminosugars against dengue virus, Adv Exp Med Biol, vol.1062, pp.277-301, 2018. ,