Animal models of obsessive-compulsive disorder: exploring pharmacology and neural substrates, Neuroscience and biobehavioral reviews, vol.36, pp.47-63, 2012. ,
Group III and subtype 4 metabotropic glutamate receptor agonists: discovery and pathophysiological applications in Parkinson's disease, Neuropharmacology, vol.66, pp.53-64, 2013. ,
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders, Proc Natl Acad Sci U S A, vol.107, pp.4389-94, 2010. ,
Studying autism in rodent models: reconciling endophenotypes with comorbidities, Front Hum Neurosci, vol.7, p.417, 2013. ,
Neural systems underlying approach and avoidance in anxiety disorders, Dialogues Clin Neurosci, vol.12, pp.517-548, 2010. ,
Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence, International review of neurobiology, vol.100, pp.13-42, 2011. ,
Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia, The Journal of comparative neurology, vol.407, pp.33-46, 1999. ,
Activation of mu-opioid receptors in the dorsal striatum is necessary for adult social attachment in monogamous prairie voles, Neuropsychopharmacology, vol.36, pp.2200-2210, 2011. ,
Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features, Mol Autism, vol.3, p.1, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-00672942
Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders, Pharmacology, biochemistry, and behavior, vol.100, pp.850-854, 2012. ,
The social motivation theory of autism, Trends Cogn Sci, vol.16, pp.231-240, 2012. ,
Modeling socially anhedonic syndromes: genetic and pharmacological manipulation of opioid neurotransmission in mice, Translational psychiatry, vol.2, p.155, 2012. ,
Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS, Neuroscience, vol.110, pp.403-423, 2002. ,
Mouse behavioral assays relevant to the symptoms of autism, Brain pathology, vol.17, pp.448-59, 2007. ,
Facial expressions of mice in aggressive and fearful contexts, Physiol Behav, vol.107, pp.680-685, 2012. ,
Progress toward treatments for synaptic defects in autism, Nature medicine, vol.19, pp.685-94, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01470299
Aberrant striatal functional connectivity in children with autism, Biological psychiatry, vol.69, pp.847-56, 2011. ,
Reward processing in autism: a thematic series, J Neurodev Disord, vol.4, p.20, 2012. ,
Reward circuitry function in autism during face anticipation and outcomes, J Autism Dev Disord, vol.42, pp.147-60, 2012. ,
Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin, Nature, vol.501, pp.179-84, 2013. ,
Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges, Behav Brain Res, vol.221, pp.50-54, 2011. ,
Translational approaches to the biology of Autism: false dawn or a new era? Molecular psychiatry, 2012. ,
Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study, Arch Gen Psychiatry, vol.69, pp.195-209, 2012. ,
Mice deficient for delta-and mu-opioid receptors exhibit opposing alterations of emotional responses, Nature genetics, vol.25, pp.195-200, 2000. ,
Opioid receptor genes inactivated in mice: the highlights, Neuropeptides, vol.36, pp.62-71, 2002. ,
Accelerated kindling development in mu-opioid receptor deficient mice, Naunyn-Schmiedeberg's archives of pharmacology, vol.369, pp.287-93, 2004. ,
Impairment in movement skills of children with autistic spectrum disorders, Dev Med Child Neurol, vol.51, pp.311-317, 2009. ,
Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [(1)H]MRS study, Translational psychiatry, vol.3, p.279, 2013. ,
, Response of the mu-opioid system to social rejection and acceptance. Molecular psychiatry, 2013.
Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice, Neuropharmacology, vol.58, pp.241-248, 2010. ,
The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior, Neuron, vol.65, pp.768-79, 2010. ,
Differential involvement of the mu and kappa opioid receptors in spatial learning, Genes Brain Behav, vol.2, pp.80-92, 2003. ,
Lack of mu-opioid receptor leads to an increase in the NMDA receptor subunit mRNA expression and NMDA-induced convulsion, Brain research Molecular brain research, vol.94, pp.105-116, 2001. ,
Identification and evaluation of children with autism spectrum disorders, Pediatrics, vol.120, pp.1183-215, 2007. ,
Autism as a neural systems disorder: a theory of frontal-posterior underconnectivity, Neuroscience and biobehavioral reviews, vol.36, pp.1292-313, 2012. ,
High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism, PLoS One, vol.7, p.35003, 2012. ,
Reward system dysfunction in autism spectrum disorders, Soc Cogn Affect Neurosci, 2012. ,
Neurochemical correlates of autistic disorder: a review of the literature, Res Dev Disabil, vol.27, pp.254-89, 2006. ,
Reward processing by the opioid system in the brain, Physiol Rev, vol.89, pp.1379-412, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00438654
Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network, Addiction biology, vol.17, pp.1-12, 2012. ,
Impaired HippocampusDependent and Facilitated Striatum-Dependent Behaviors in Mice Lacking the Delta Opioid Receptor, Neuropsychopharmacology, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02266437
Summary of the comparative effectiveness review on off-label use of atypical antipsychotics, Journal of managed care pharmacy, vol.18, pp.1-20, 2012. ,
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene, Nature, vol.383, pp.819-842, 1996. ,
Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders, Journal of abnormal child psychology, vol.41, pp.165-76, 2013. ,
Deficit in attachment behavior in mice lacking the mu-opioid receptor gene, Science, vol.304, pp.1983-1989, 2004. ,
Neurobiological correlates of social functioning in autism, Clinical psychology review, vol.30, pp.733-781, 2010. ,
Monogenic mouse models of social dysfunction: implications for autism, Behav Brain Res, vol.251, pp.75-84, 2013. ,
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction, Nature, vol.472, pp.437-479, 2011. ,
Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits, Cell, vol.147, pp.235-281, 2011. ,
Test-specific effects of FG-7142 on isolation-induced aggression in mice, Pharmacology, biochemistry, and behavior, vol.42, pp.317-338, 1992. ,
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders, J Child Psychol Psychiatry, vol.52, pp.442-75, 2011. ,
Childhood epilepsy and autism spectrum disorders: psychiatric problems, phenotypic expression, and anticonvulsants, Neuropsychology review, vol.22, pp.271-280, 2012. ,
Decreased left perisylvian GABA concentration in children with autism and unaffected siblings, Neuroimage, 2013. ,
mu-Opioid receptor-knockout mice: the role of mu-opioid receptor in gastrointestinal transit, Brain research Molecular brain research, vol.56, pp.281-284, 1998. ,
, SHANK1 Deletions in Males with Autism Spectrum Disorder, vol.90, pp.879-87, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-01580198
Anxiolytic-but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu(4) receptor, Neuropharmacology, vol.66, pp.225-260, 2013. ,
The conundrums of understanding genetic risks for autism spectrum disorders, Nat Neurosci, vol.14, pp.1499-506, 2011. ,
Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat, J Neurosci, vol.14, pp.3005-3023, 1994. ,
The pleasures of play: pharmacological insights into social reward mechanisms, Trends in pharmacological sciences, vol.31, pp.463-472, 2010. ,
Nucleus accumbens muopioid receptors mediate social reward, J Neurosci, vol.31, pp.6362-70, 2011. ,
Social hedonic capacity is associated with the A118G polymorphism of the mu-opioid receptor gene (OPRM1) in adult healthy volunteers and psychiatric patients, Social neuroscience, vol.6, pp.88-97, 2011. ,
Animal models of obsessive-compulsive disorder: exploring pharmacology and neural substrates, Neuroscience and biobehavioral reviews, vol.36, pp.47-63, 2012. ,
Group III and subtype 4 metabotropic glutamate receptor agonists: discovery and pathophysiological applications in Parkinson's disease, Neuropharmacology, vol.66, pp.53-64, 2013. ,
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders, Proc Natl Acad Sci U S A, vol.107, pp.4389-94, 2010. ,
Studying autism in rodent models: reconciling endophenotypes with comorbidities, Front Hum Neurosci, vol.7, p.417, 2013. ,
Neural systems underlying approach and avoidance in anxiety disorders, Dialogues Clin Neurosci, vol.12, pp.517-548, 2010. ,
Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence, International review of neurobiology, vol.100, pp.13-42, 2011. ,
Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia, The Journal of comparative neurology, vol.407, pp.33-46, 1999. ,
Activation of mu-opioid receptors in the dorsal striatum is necessary for adult social attachment in monogamous prairie voles, Neuropsychopharmacology, vol.36, pp.2200-2210, 2011. ,
Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features, Mol Autism, vol.3, p.1, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-00672942
Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders, Pharmacology, biochemistry, and behavior, vol.100, pp.850-854, 2012. ,
The social motivation theory of autism, Trends Cogn Sci, vol.16, pp.231-240, 2012. ,
Modeling socially anhedonic syndromes: genetic and pharmacological manipulation of opioid neurotransmission in mice, Translational psychiatry, vol.2, p.155, 2012. ,
Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS, Neuroscience, vol.110, pp.403-423, 2002. ,
Mouse behavioral assays relevant to the symptoms of autism, Brain pathology, vol.17, pp.448-59, 2007. ,
Facial expressions of mice in aggressive and fearful contexts, Physiol Behav, vol.107, pp.680-685, 2012. ,
Progress toward treatments for synaptic defects in autism, Nature medicine, vol.19, pp.685-94, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01470299
Aberrant striatal functional connectivity in children with autism, Biological psychiatry, vol.69, pp.847-56, 2011. ,
Reward processing in autism: a thematic series, J Neurodev Disord, vol.4, p.20, 2012. ,
Reward circuitry function in autism during face anticipation and outcomes, J Autism Dev Disord, vol.42, pp.147-60, 2012. ,
Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin, Nature, vol.501, pp.179-84, 2013. ,
Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges, Behav Brain Res, vol.221, pp.50-54, 2011. ,
Translational approaches to the biology of Autism: false dawn or a new era? Molecular psychiatry, 2012. ,
Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study, Arch Gen Psychiatry, vol.69, pp.195-209, 2012. ,
Mice deficient for delta-and mu-opioid receptors exhibit opposing alterations of emotional responses, Nature genetics, vol.25, pp.195-200, 2000. ,
Opioid receptor genes inactivated in mice: the highlights, Neuropeptides, vol.36, pp.62-71, 2002. ,
Accelerated kindling development in mu-opioid receptor deficient mice, Naunyn-Schmiedeberg's archives of pharmacology, vol.369, pp.287-93, 2004. ,
Impairment in movement skills of children with autistic spectrum disorders, Dev Med Child Neurol, vol.51, pp.311-317, 2009. ,
Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [(1)H]MRS study, Translational psychiatry, vol.3, p.279, 2013. ,
, Response of the mu-opioid system to social rejection and acceptance. Molecular psychiatry, 2013.
Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice, Neuropharmacology, vol.58, pp.241-248, 2010. ,
The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior, Neuron, vol.65, pp.768-79, 2010. ,
Differential involvement of the mu and kappa opioid receptors in spatial learning, Genes Brain Behav, vol.2, pp.80-92, 2003. ,
Lack of mu-opioid receptor leads to an increase in the NMDA receptor subunit mRNA expression and NMDA-induced convulsion, Brain research Molecular brain research, vol.94, pp.105-116, 2001. ,
Identification and evaluation of children with autism spectrum disorders, Pediatrics, vol.120, pp.1183-215, 2007. ,
Autism as a neural systems disorder: a theory of frontal-posterior underconnectivity, Neuroscience and biobehavioral reviews, vol.36, pp.1292-313, 2012. ,
High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism, PLoS One, vol.7, p.35003, 2012. ,
Reward system dysfunction in autism spectrum disorders, Soc Cogn Affect Neurosci, 2012. ,
Neurochemical correlates of autistic disorder: a review of the literature, Res Dev Disabil, vol.27, pp.254-89, 2006. ,
Reward processing by the opioid system in the brain, Physiol Rev, vol.89, pp.1379-412, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00438654
Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network, Addiction biology, vol.17, pp.1-12, 2012. ,
Impaired HippocampusDependent and Facilitated Striatum-Dependent Behaviors in Mice Lacking the Delta Opioid Receptor, Neuropsychopharmacology, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02266437
Summary of the comparative effectiveness review on off-label use of atypical antipsychotics, Journal of managed care pharmacy, vol.18, pp.1-20, 2012. ,
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene, Nature, vol.383, pp.819-842, 1996. ,
Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders, Journal of abnormal child psychology, vol.41, pp.165-76, 2013. ,
Deficit in attachment behavior in mice lacking the mu-opioid receptor gene, Science, vol.304, pp.1983-1989, 2004. ,
Neurobiological correlates of social functioning in autism, Clinical psychology review, vol.30, pp.733-781, 2010. ,
Monogenic mouse models of social dysfunction: implications for autism, Behav Brain Res, vol.251, pp.75-84, 2013. ,
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction, Nature, vol.472, pp.437-479, 2011. ,
Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits, Cell, vol.147, pp.235-281, 2011. ,
Reactive/proactive aggression and affective/cognitive empathy in children with ASD, Res Dev Disabil, vol.34, pp.1256-66, 2013. ,
Test-specific effects of FG-7142 on isolation-induced aggression in mice, Pharmacology, biochemistry, and behavior, vol.42, pp.317-338, 1992. ,
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders, J Child Psychol Psychiatry, vol.52, pp.442-75, 2011. ,
Childhood epilepsy and autism spectrum disorders: psychiatric problems, phenotypic expression, and anticonvulsants, Neuropsychology review, vol.22, pp.271-280, 2012. ,
Decreased left perisylvian GABA concentration in children with autism and unaffected siblings, Neuroimage, 2013. ,
mu-Opioid receptor-knockout mice: the role of mu-opioid receptor in gastrointestinal transit, Brain research Molecular brain research, vol.56, pp.281-284, 1998. ,
, SHANK1 Deletions in Males with Autism Spectrum Disorder, vol.90, pp.879-87, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-01580198
Anxiolytic-but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu(4) receptor, Neuropharmacology, vol.66, pp.225-260, 2013. ,
The conundrums of understanding genetic risks for autism spectrum disorders, Nat Neurosci, vol.14, pp.1499-506, 2011. ,
Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat, J Neurosci, vol.14, pp.3005-3023, 1994. ,
The pleasures of play: pharmacological insights into social reward mechanisms, Trends in pharmacological sciences, vol.31, pp.463-472, 2010. ,
Nucleus accumbens muopioid receptors mediate social reward, J Neurosci, vol.31, pp.6362-70, 2011. ,
Social hedonic capacity is associated with the A118G polymorphism of the mu-opioid receptor gene (OPRM1) in adult healthy volunteers and psychiatric patients, Social neuroscience, vol.6, pp.88-97, 2011. ,
Cellular activation in limbic brain systems during social play behaviour in rats, Brain Struct Funct, 2013. ,
Networking in autism: leveraging genetic, biomarker and model system findings in the search for new treatments, Neuropsychopharmacology, vol.37, pp.196-212, 2012. ,
Variation in the mu-opioid receptor gene (OPRM1) is associated with dispositional and neural sensitivity to social rejection, Proc Natl Acad Sci U S A, vol.106, pp.15079-84, 2009. ,
Social experience induces sex-specific fos expression in the amygdala of the juvenile rat, Horm Behav, vol.62, pp.154-61, 2012. ,
Social anxiety mediates the effect of autism spectrum disorder characteristics on hostility in young adults, Autism, vol.16, pp.453-64, 2012. ,
Sensory-motor problems in Autism, Frontiers in integrative neuroscience, vol.7, p.51, 2013. ,
Lack of social exploratory activation in male mu-opioid receptor KO mice in response to playback of female ultrasonic vocalizations, Soc Neurosci, vol.6, pp.76-87, 2011. ,
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function, Nature, vol.486, pp.261-266, 2012. ,