Massive increase in monocyte HLA-DR expression can be used to discriminate between septic shock and hemophagocytic lymphohistiocytosis-induced shock

Résumé : Clinical presentations of hemophagocytic lymphohistiocytosis (HLH) and septic shock share many similarities, including multiple organ dysfunction and overall clinical and biological symptoms. However, these life-threatening conditions require specific and opposing treatments. Currently, no single biomarker is available to differentiate septic shock from HLH at patient admission
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Solenn Remy, Morgane Gossez, Alexandre Belot, Jack Hayman, Aurelie Portefaix, et al.. Massive increase in monocyte HLA-DR expression can be used to discriminate between septic shock and hemophagocytic lymphohistiocytosis-induced shock. Critical Care, BioMed Central, 2018, 22 (213), 2 p. ⟨10.1186/s13054-018-2146-2⟩. ⟨hal-02266062⟩

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