Skip to Main content Skip to Navigation
Journal articles

Bulk pollen sequencing reveals rapid evolution of segregation distortion in the male germline of Arabidopsis hybrids

Abstract : Genes that do not segregate in heterozygotes at Mendelian ratios are a potentially important evolutionary force in natural populations. Although the impacts of segregation distortion are widely appreciated, we have little quantitative understanding about how often these loci arise and fix within lineages. Here, we develop a statistical approach for detecting segregation distorting genes from the comprehensive comparison of whole genome sequence data obtained from bulk gamete versus somatic tissues. Our approach enables estimation of map positions and confidence intervals, and quantification of effect sizes of segregation distorters. We apply our method to the pollen of two interspecific F1 hybrids of Arabidopsis lyrata and A. halleri and we identify three loci across eight chromosomes showing significant evidence of segregation distortion in both pollen samples. Based on this, we estimate that novel segregation distortion elements evolve and achieve high frequencies within lineages at a rate of approximately one per 244,000 years. Furthermore, we estimate that haploid-acting segregation distortion may contribute between 10% and 30% of reduced pollen viability in F1 individuals. Our results indicate haploid acting factors evolve rapidly and dramatically influence segregation in F1 hybrid individuals.
Complete list of metadatas

Cited literature [43 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-02265360
Contributor : Anne-Gestion Labo Duputié <>
Submitted on : Friday, August 9, 2019 - 2:40:19 PM
Last modification on : Saturday, August 10, 2019 - 1:18:08 AM
Document(s) archivé(s) le : Thursday, January 9, 2020 - 12:43:23 PM

File

Corbett-Detig et al. - 2019 - ...
Publisher files allowed on an open archive

Identifiers

Collections

Citation

Russell Corbett-Detig, Paloma Medina, Hélène Frerot, Christelle Blassiau, Vincent Castric. Bulk pollen sequencing reveals rapid evolution of segregation distortion in the male germline of Arabidopsis hybrids. Evolution Letters, Wiley Open Access 2019, 3 (1), pp.93-103. ⟨10.1002/evl3.96⟩. ⟨hal-02265360⟩

Share

Metrics

Record views

71

Files downloads

56