Use of a Synthetic Biosensor for Neutralizing Activity-Biased Selection of Monoclonal Antibodies against Atroxlysin-I, an Hemorrhagic Metalloproteinase from Bothrops atrox Snake Venom

Francisco Santos Schneider (1) , Dung Le Nguyen , Karen Larissa Castro , Sandra Cobo (1) , Ricardo Andrez Machado de Avila , Nivia de Assis Ferreira , Eladio Flores Sanchez , Christophe Nguyen (1) , Claude Granier (2) , Pascale Galea (1) , Carlos Chávez-Olortegui , Franck Molina (1) , José María Gutiérrez

1 Sys2Diag - Sys2Diag-Modélisation et Ingénierie des Systèmes Complexes Biologiques pour le Diagnostic
2 UMR 9921

Domaines: Sciences du Vivant [q-bio]

Francisco Santos Schneider, Dung Le Nguyen, Karen Larissa Castro, Sandra Cobo, Ricardo Andrez Machado de Avila, et al.. Use of a Synthetic Biosensor for Neutralizing Activity-Biased Selection of Monoclonal Antibodies against Atroxlysin-I, an Hemorrhagic Metalloproteinase from Bothrops atrox Snake Venom. PLoS Neglected Tropical Diseases, 2014, 8 (4), pp.e2826. ⟨10.1371/journal.pntd.0002826⟩. ⟨hal-02203402⟩