Thermolytic Reagents to Synthesize 5′- or 3′-Mono(thio)phosphate Oligodeoxynucleotides or 3′-modified oligodeoxynucleotides

Mimouna Madaoui (1) , Albert Meyer (1) , Jean-Jacques Vasseur (1) , François Morvan (1)

1 IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]

Mots clés: OLIGONUCLEOTIDES; OLIGODEOXYRIBONUCLEOTIDES; RNA INTERFERENCE; PROTECTING GROUPS; SOLID-PHASE SYNTHESIS; CHEMICAL PHOSPHORYLATION

Domaines: Chimie; Chimie organique; Chimie thérapeutique; Chimie analytique

Mimouna Madaoui, Albert Meyer, Jean-Jacques Vasseur, François Morvan. Thermolytic Reagents to Synthesize 5′- or 3′-Mono(thio)phosphate Oligodeoxynucleotides or 3′-modified oligodeoxynucleotides. European Journal of Organic Chemistry, 2019, 2019 (17), pp.2832-2842. ⟨10.1002/ejoc.201900302⟩. ⟨hal-02197142⟩