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Fat-soluble micronutrients and metabolic syndrome

Abstract : Purpose of review Metabolic syndrome (MetS) is associated with increased risk of obesity, type 2 diabetes mellitus and cardiovascular diseases. MetS prevalence has been associated with diet inadequacy. Conversely, the cumulative incidence of MetS has been inversely associated with a Mediterranean-style diet that includes many different health-beneficial nutrients. Adherence to a Mediterranean-style diet could reduce or at least stabilize metabolic risk factors. Recent findings Low serum level of fat-soluble micronutrients, such as carotenoids, vitamin (vit) A, D and E, has been linked to MetS. Fat-soluble micronutrients could contribute to prevent MetS thanks to their antioxidant and anti-inflammatory properties (vit E, carotenoids) or to their central role as hormone regulators (vit D) and/or lipid metabolism and glucose homeostasis sensors (vit D and E). Summary This review summarizes recent epidemiological studies linking fat-soluble micronutrients to MetS and highlights new evidence on their mechanisms of actions.
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https://hal.archives-ouvertes.fr/hal-02176174
Contributor : Aurélie Goncalves <>
Submitted on : Sunday, July 7, 2019 - 6:18:33 PM
Last modification on : Friday, July 17, 2020 - 3:46:19 PM

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Aurélie Goncalves, Marie-Josèphe Amiot. Fat-soluble micronutrients and metabolic syndrome. Current Opinion in Clinical Nutrition and Metabolic Care, Lippincott, Williams & Wilkins, 2017, 20 (6), pp.1. ⟨10.1097/MCO.0000000000000412⟩. ⟨hal-02176174⟩

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