R. Baelmans, E. Deharo, V. Muñoz, M. Sauvain, and H. Ginsburg, Experimental conditions for testing the inhibitory activity of chloroquine on the formation of b-haematin, Experimental Parasitology, vol.96, pp.243-248, 2000.

N. Basilico, E. Pagani, D. Monti, P. Olliaro, and D. Taramelli, A microtitre-based method for measuring the haem polymerisation inhibitory activity (HPIA) of antimalarial drugs, The Journal of Antimicrobial Chemotherapy, vol.42, pp.55-60, 1998.

C. Cereser, J. Guichard, J. Drai, E. Bannier, I. Garcia et al., Quantitation of reduced and total glutathione at the femtomole level by high-performance liquid chromatography with Xuorescence detection: application to red blood cells and cultured Wbroblasts, Journal of Chromatography, vol.752, pp.123-132, 2001.

V. H. Cohn and J. Lyle, A Xuorometric assay for glutathione, Analytical Biochemistry, vol.14, pp.434-440, 1966.

E. Deharo, R. Garcia, P. Oporto, M. Sauvain, P. Gautret et al., A non-radiolabeled ferriprotoporphyrin IX biomineralization inhibition test (FBIT) for the high throughput screening of antimalarial compounds, Experimental Parasitology, vol.100, pp.252-256, 2002.

U. Eckstein-ludwig, R. J. Webb, I. D. Van-goethem, J. M. East, A. G. Lee et al., Artemisinins target the SERCA of Plasmodium falciparum, Nature, vol.424, pp.887-889, 2003.

H. Ginsburg, O. Famin, J. Zhang, and M. Krugliak, Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action, Biochemical Pharmacology, vol.56, pp.1305-1313, 1998.

P. J. Hissin and R. Hilf, A Xuorometric method for determination of oxidized and reduced glutathione in tissues, Analytical Biochemistry, vol.74, pp.214-226, 1976.

Y. Kurosawa, A. Dorn, M. Kitsuji-shirane, H. Shimada, T. Satoh et al., Hematin polymerisation assay as a high-throughput screen for identiWcation of new antimalarial pharmacophores, Antimicrobial Agents and Chemotherapy, vol.44, pp.2638-2644, 2000.

M. W. Mather, E. Darrouzet, M. Valkova-valchanova, J. W. Cooley, M. T. Mcintosh et al., Uncovering the molecular mode of action of the antimalarial drug atovaquone using a bacterial system, The Journal of Biological Chemistry, vol.280, issue.29, pp.27458-27465, 2005.

S. R. Meshnick, Artemisinin: mechanisms of action, resistance and toxicity, International Journal for Parasitology, vol.32, pp.1655-1660, 2002.

B. A. Neuschwander-tetri and F. J. Roll, Glutathione measurement by high-performance liquid chromatography separation and Xuorometric detection of the glutathione-orthophthalaldehyde adduct, Analytical Biochemistry, vol.179, pp.236-241, 1989.

R. C. Scaduto, Dithiothreitol and amino acids interfere with the Xuorometric determination of glutathione with orthophthaldehyde, Analytical Biochemistry, vol.174, issue.1, pp.265-270, 1988.

J. C. Steele, R. J. Phelps, M. S. Simmonds, D. C. Warhurst1, and D. J. Meyer, Two novel assays for the detection of heme-binding properties of antimalarials evaluated with compounds isolated from medicinal plants, Journal of Antimicrobial Chemotherapy, vol.50, pp.25-31, 2002.

M. Wainwright and L. Amaral, The phenothiazinium chromophore and the evolution of antimalarial drugs, Tropical Medicine & International Health, vol.10, pp.501-511, 2005.

. Who-tdr, The World Health Organization, Special Programme for Research and Training in Tropical Diseases, 2006.