Constant gradient magnetic resonance elastography experiments on phantom and bovine liver.

Pilar Sango Solanas (1) , Eric Van Reeth , Pauline Lefebvre (1) , Hélène Ratiney (1) , Elisabeth Brusseau (2) , Denis Grenier (3) , Steffen Glaser (4) , Dominique Sugny (5) , Olivier Beuf (1) , Kevin Tse-Ve-Koon (1)

1 RMN et optique : De la mesure au biomarqueur
2 Imagerie Ultrasonore
3 PILoT - Plateforme d'Imagerie Multimodale LyonTech
4 Department of Chemistry [Munich]
5 ICB - Laboratoire Interdisciplinaire Carnot de Bourgogne

Synopsis Magnetic Resonance Elastography (MRE) is performed by the application of motion-sensitive gradients. In this study, RF pulses are designed with an optimal control algorithm to obtain a desired magnetization phase distribution. Such pulse, in presence of a constant gradient, allows to simultaneously perform spatially selective excitation and motion encoding. This offers some advantages when compared to standard MRE encoding strategy. Simulations, phantom and ex vivo experiments show that phase-to-noise ratios are improved. These results demonstrate that optimal control-based pulses can be used to encode motion in the MRE excitation phase with relevant advantages for further in vivo liver rat studies.

Domaines: Imagerie

Pilar Sango Solanas, Eric Van Reeth, Pauline Lefebvre, Hélène Ratiney, Elisabeth Brusseau, et al.. Constant gradient magnetic resonance elastography experiments on phantom and bovine liver.. ISMRM 2019 27th Annual Meeting & Exhibition, May 2019, Montréal, Canada. ⟨hal-02142513⟩