Synthesis of ribavirin 2’-Me-C-nucleoside analogues
Résumé
An efficient synthetic pathway leading to two carbonated analogues of ribavirin is described. The key-steps in the synthesis of these ribosyltriazoles bearing a quaternary carbon atom in the 2'-position are an indium-mediated alkynylation and a 1,3-dipolar cyclization.
Domaines
Chimie
Origine : Fichiers produits par l'(les) auteur(s)