Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm

Patricia Santofimia-Castaño (1) , Bruno Rizzuti (2) , Yi Xia (3) , Olga Abián (4) , Ling Peng (5) , Adrián Velázquez-Campoy (4) , Juan Iovanna (1) , José L Neira (6)

1 CRCM - Centre de Recherche en Cancérologie de Marseille
2 Department of Physics - CNR-NANOTEC, Licryl-UOS Cosenza & CEMIF.Cal [Cosenza, Italy]
3 Chongqing University [Chongqing]
4 Unidad Asociada IQFR-CSIC-BIFI [Zaragoza, Spain]
5 CINaM - Centre Interdisciplinaire de Nanoscience de Marseille
6 Instituto de Biología Molecular y Celular [Alicante, Spain]

Domaines: Chimie; Sciences du Vivant [q-bio]

Patricia Santofimia-Castaño, Bruno Rizzuti, Yi Xia, Olga Abián, Ling Peng, et al.. Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm. Molecular & Cellular Oncology, 2019, pp.1-3. ⟨10.1080/23723556.2019.1612678⟩. ⟨hal-02140372⟩