Transcriptional expression of mannose receptor gene during differentiation of human macrophages.

Abstract : Mannose receptor is a differentiation marker of macrophages. Circulating monocytes isolated from plasma are devoid of this receptor; upon culture this receptor is rapidly expressed. Its expression is modulated by a variety of inflammatory and anti-inflammatory agents. In the present study, we investigated its transcription level during the differentiation process. Mannose receptor mRNA was monitored by quantitative RT-PCR on freshly harvested monocytes and on monocytes cultivated up to four days. No transcription was detected in freshly harvested cells, the transcription increased during the first 24 h upon adhesion and then decreased.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-02138393
Contributor : Laëtitia Legoupil <>
Submitted on : Thursday, May 23, 2019 - 5:36:47 PM
Last modification on : Friday, May 24, 2019 - 8:46:02 AM

Identifiers

  • HAL Id : hal-02138393, version 1
  • PUBMED : 8526897

Collections

Citation

F Rouleux-Bonnin, M. Monsigny, Alain Legrand. Transcriptional expression of mannose receptor gene during differentiation of human macrophages.. Biochemical and Biophysical Research Communications, Elsevier, 1995, 217 (1), pp.106-12. ⟨hal-02138393⟩

Share

Metrics

Record views

13