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Effet antimicrobien et sur le mal de gorge d’un spray à base d’extraits de sauge et de sureau, d’huile essentielle de menthe poivrée, de miel et de zinc

Abstract : Sore throat is one of the most common reasons for consultation in general medicine. Besides the usual allopathic drugs, phytotherapy can be envisaged for its management. To assess the relevance of a product combining extracts of sage and elder, peppermint essential oil, honey and zinc for the management of sore throat, its effect was evaluated in vitro against the main pathogens involved in sore throat (broth microdilution method) and in a prospective observational study carried out in pharmacies. Bactericidal activity was observed against all Gram-negative (Branhamella catarrhalis, Fusobacterium nucleatum and Haemophilus influenzae) and Gram-positive (Streptococcus pyogenes) bacteria strains; antiviral activity was also tested against type 3 para-influenzae virus. Product activity was maintained at 1:64 dilution ratio. Data collected during the observational study suggest that the product can relieve pain and other symptoms such as dry throat sensation and erythema within 17 minutes on average after spraying. While eliminating possible pathogens involved, the product could relieve pain and symptoms associated with sore throat. These results will have to be confirmed in a clinical trial.
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Submitted on : Monday, May 20, 2019 - 5:24:38 PM
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B. Deyra, I. Guinobert, C. Feuillolay, L. Haddioui, Christine Roques, et al.. Effet antimicrobien et sur le mal de gorge d’un spray à base d’extraits de sauge et de sureau, d’huile essentielle de menthe poivrée, de miel et de zinc. Phytothérapie, Springer Verlag, 2017, 15 (4), pp.203-210. ⟨10.1007/s10298-017-1155-7⟩. ⟨hal-02134814⟩

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