HYPOXIA-TARGETED DELIVERY SYSTEM FOR PHARMACEUTICAL AGENTS

Abstract : Molecular compositions, nanoparticle compositions, and pharmaceutical compositions of the invention provide for the delivery of a polynucleotide to a hypoxic cell or tissue. The compositions can also be used for the delivery a hydrophobic pharmaceutical agent, either alone or in combination with a polynucleotide, to a hypoxic cell or tissue. Methods of making such compositions and methods of using such composition to treat a condition associated with a hypoxic cell or tissue are provided as well. Also provideded are kits for use in treating a condition associated with a hypoxic cell or tissue.
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Patents
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https://hal.archives-ouvertes.fr/hal-02130900
Contributor : Laëtitia Legoupil <>
Submitted on : Thursday, May 16, 2019 - 10:41:53 AM
Last modification on : Thursday, May 16, 2019 - 10:41:53 AM

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  • HAL Id : hal-02130900, version 1

Citation

Vladimir Torchilin, Swati Biswas, Federico Perche. HYPOXIA-TARGETED DELIVERY SYSTEM FOR PHARMACEUTICAL AGENTS. France, Patent n° : WO2015061321. 2015. ⟨hal-02130900⟩

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