Pre-clinical fatty acid composition estimate of adipose tissue using echo planar spectroscopic imaging (EPSI) at 4.7T

Angeline Nemeth (1) , Sophie Gaillard (2) , O. Beuf (1) , Hélène Ratiney (1)

1 RMN et optique : De la mesure au biomarqueur
2 PILoT - Plateforme d'Imagerie Multimodale LyonTech

This pilot study performed on a preclinical system at 4.7T shows the feasibility of using the echo planar spectroscopic imaging sequence (EPSI with a spin echo) to quantify the fatty acid composition. This sequence permitted to image separately each resonating component of fat spectrum. The signal of the EPSI sequence was compared with more standard spectroscopic sequence used for the fatty acid quantification (PRESS). The quantification results from the EPSI sequence on calibrated phantom were consistent with gas chromatography theoretical values. The in vivo acquisition showed a significant difference of the fatty acid composition between the subcutaneous and the visceral adipose tissue, consistent with published monovoxel results. Abstract available: https://index.mirasmart.com/ISMRM2019/PDFfiles/1937.html

Domaines: Imagerie

Angeline Nemeth, Sophie Gaillard, O. Beuf, Hélène Ratiney. Pre-clinical fatty acid composition estimate of adipose tissue using echo planar spectroscopic imaging (EPSI) at 4.7T. 27th Annual meeting of the ISMRM, May 2019, Montreal, Canada. ⟨hal-02129970⟩