Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo

Lotfi Bounaadja (1) , Marjorie Schmitt (2) , Sébastien Albrecht (3) , Elisabeth Mouray (1) , Céline Tarnus (1) , Isabelle Florent (1)

1 MCAM - Molécules de Communication et Adaptation des Micro-organismes
2 LCM - Laboratoire de chimie moléculaire
3 COB - Laboratoire de Chimie organique et bioorganique

Domaines: Chimie; Sciences du Vivant [q-bio]

Lotfi Bounaadja, Marjorie Schmitt, Sébastien Albrecht, Elisabeth Mouray, Céline Tarnus, et al.. Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo. Malaria Journal, 2017, 16 (1), ⟨10.1186/s12936-017-2032-4⟩. ⟨hal-02126893⟩