On mechanically driven biological stimulus for bone remodeling as a diffusive phenomenon

Ivan Giorgio (1, 2) , Francesco Dell'Isola (2) , Ugo Andreaus (1) , Faris Alzahrani (3) , Tasawar Hayat (3) , Tomasz Lekszycki (4, 5, 2)

1 DISG - Dipartimento di Ingegneria Strutturale e Geotecnica
2 MEMOCS - International Research Center for the Mathematics & Mechanics of Complex Systems
3 King Abdulaziz University
4 Warsaw University of Technology [Warsaw]
5 Department of Experimental Physiology and Pathophysiology, Medical University of Warsaw

In the past years, many attempts have been made in order to model the process of bone remodeling. This process is complex, as it is governed by not yet completely understood biomechanical coupled phenomena. It is well known that bone tissue is able to self-adapt to different environmental demands of both mechanical and biological origin. The mechanical aspects are related to the functional purpose of the bone tissue, i.e., to provide support to the body and protection for the vitally important organs in response to the external loads. The many biological aspects include the process of oxygen and nutrients supply. To describe the biome-chanical process of functional adaptation of bone tissue, the approach commonly

Domaines: Génie mécanique [physics.class-ph]; Biomécanique [physics.med-ph]

Ivan Giorgio, Francesco Dell'Isola, Ugo Andreaus, Faris Alzahrani, Tasawar Hayat, et al.. On mechanically driven biological stimulus for bone remodeling as a diffusive phenomenon. Biomechanics and Modeling in Mechanobiology, 2019, ⟨10.1007/s10237-019-01166-w⟩. ⟨hal-02125369⟩