New functional domains of human cytomegalovirus pUL89 predicted by sequence analysis and three-dimensional modelling of the catalytic site DEXDc.

Abstract : Benzimidazole D-ribonucleosides inhibit DNA packaging during human cytomegalovirus (HCMV) replication. Although they have been shown to target pUL56 and pUL89, the large and small subunits of the HCMV terminase respectively, their mechanism of action is not yet fully understood.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-02122527
Contributor : Serge Bouaziz <>
Submitted on : Tuesday, May 7, 2019 - 2:03:40 PM
Last modification on : Thursday, May 9, 2019 - 2:48:08 PM

Identifiers

  • HAL Id : hal-02122527, version 1
  • PUBMED : 17503664

Citation

Gaël Champier, Sébastien Hantz, Anthony Couvreux, Stéphanie Stuppfler, Marie-Christine Mazeron, et al.. New functional domains of human cytomegalovirus pUL89 predicted by sequence analysis and three-dimensional modelling of the catalytic site DEXDc.. Antiviral Therapy, International Medical Press, 2019, 12 (2), pp.217-32. ⟨hal-02122527⟩

Share

Metrics

Record views

34