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Article Dans Une Revue Trends in Biochemical Sciences Année : 2002

Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases

Résumé

Diacylglyceride kinases, sphingosine kinases, NAD kinases and 6-phosphofructokinases are thought to be related despite large evolution of their sequences. Discovery of a common signature has led to the suggestion that they possess a similar phosphate-donor-binding site and a similar phosphorylation mechanism. The substrate- and allosteric-binding sites are much more divergent and their delineation remains to be determined experimentally.

Dates et versions

hal-02115578 , version 1 (30-04-2019)

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Citer

Gilles Labesse, Dominique Douguet, Liliane Assairi, Anne-Marie Gilles. Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases. Trends in Biochemical Sciences, 2002, 27 (6), pp.273-275. ⟨10.1016/S0968-0004(02)02093-5⟩. ⟨hal-02115578⟩
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