Skip to Main content Skip to Navigation
Journal articles

A recent bottleneck of Y chromosome diversity coincides with a global change in culture

Monika Karmin Lauri Saag Mário Vicente Melissa Wilson Sayres Mari Järve Ulvi Gerst Talas Siiri Rootsi 1 Anne-Mai Ilumäe Reedik Mägi Mario Mitt Luca Pagani Tarmo Puurand Zuzana Faltyskova Florian Clemente Alexia Cardona Ene Metspalu 2 Hovhannes Sahakyan Bayazit Yunusbayev Georgi Hudjashov Michael Degiorgio Eva-Liis Loogväli Chris Eichstaedt Mikk Eelmets Gyaneshwer Chaubey Kristiina Tambets Sergei Litvinov Maru Mormina 3 Yali Xue 4 Qasim Ayub Grigor Zoraqi Thorfinn Sand Korneliussen Farida Akhatova Joseph Lachance Sarah Tishkoff 5 Kuvat Momynaliev François-Xavier Ricaut 6, 7 Pradiptajati Kusuma 8 Harilanto Razafindrazaka 9 Denis Pierron 8 Murray Cox Gazi Nurun Nahar Sultana Rane Willerslev Craig Muller Michael Westaway David Lambert 10 Vedrana Skaro Lejla Kovačevic Shahlo Turdikulova Dilbar Dalimova Rita Khusainova Natalya Trofimova Vita Akhmetova Irina Khidiyatova Daria Lichman Jainagul Isakova 11 Elvira Pocheshkhova Zhaxylyk Sabitov Nikolay Barashkov Pagbajabyn Nymadawa 12 Evelin Mihailov Joseph Wee Tien Seng Irina Evseeva 13 Andrea Migliano Syafiq Abdullah George Andriadze Dragan Primorac Lubov Atramentova Olga Utevska Levon Yepiskoposyan Damir Marjanovic Alena Kushniarevich Doron Behar Chris Gilissen Lisenka Vissers 14 Joris Veltman 15 Elena Balanovska Miroslava Derenko Boris Malyarchuk Andres Metspalu 16 Sardana Fedorova Anders Eriksson 17 Andrea Manica Fernando Méndez 18 Tatiana Karafet Krishna Veeramah Neil Bradman Michael Hammer Ludmila Osipova 19 Oleg Balanovsky 20 Elza Khusnutdinova 21 Knut Johnsen Maido Remm Mark Thomas Chris Tyler-Smith 22 Peter Underhill 23 Eske Willerslev 24 Rasmus Nielsen 25 Mait Metspalu 2 Richard Villems 26 Toomas Kivisild 3 Melissa Sayres Mari Mitt Christina Eichstaedt Lejla Kovačevic´ Joseph Seng Andrea Bamberg Migliano Damir Marjanovic´ Christian Gilissen 15
Abstract : It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192-307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47-52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
Document type :
Journal articles
Complete list of metadata

Cited literature [51 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-02112784
Contributor : Francois-Xavier Ricaut Connect in order to contact the contributor
Submitted on : Tuesday, October 1, 2019 - 5:25:08 PM
Last modification on : Thursday, November 18, 2021 - 4:36:19 PM

File

Genome Res.-2015-Karmin-459-66...
Publisher files allowed on an open archive

Identifiers

Collections

Citation

Monika Karmin, Lauri Saag, Mário Vicente, Melissa Wilson Sayres, Mari Järve, et al.. A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Genome Research, Cold Spring Harbor Laboratory Press, 2015, 25 (4), pp.459-466. ⟨10.1101/gr.186684.114⟩. ⟨hal-02112784⟩

Share

Metrics

Les métriques sont temporairement indisponibles