3‘-Ferrocene-Labeled Oligonucleotide Chains End-Tethered to Gold Electrode Surfaces: Novel Model Systems for Exploring Flexibility of Short DNA Using Cyclic Voltammetry

Abstract : The flexibility of DNA is of central importance in biology, medicine, materials science, and mechanical engineering. In this study, we report an unprecedented electrochemical approach for investigating the flexibility of a short (typically 20-base), surface end-tethered single-stranded synthetic DNA oligonucleotide and of its postformed DNA duplex, taking as an example the homopolymer (dT)20 sequence in the regime of very high ionic strength ( approximately 1 M).
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-02107117
Contributor : Agnès Pallier <>
Submitted on : Tuesday, April 23, 2019 - 3:15:28 PM
Last modification on : Thursday, April 25, 2019 - 1:24:50 AM

Links full text

Identifiers

Collections

Citation

Agnès Anne, Agnès Bouchardon, Jacques Moiroux. 3‘-Ferrocene-Labeled Oligonucleotide Chains End-Tethered to Gold Electrode Surfaces: Novel Model Systems for Exploring Flexibility of Short DNA Using Cyclic Voltammetry. Journal of the American Chemical Society, American Chemical Society, 2003, 125 (5), pp.1112-1113. ⟨10.1021/ja028640k⟩. ⟨hal-02107117⟩

Share

Metrics

Record views

23