Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].

Vincent Aucagne (1) , Franck Amblard , Luigi Agrofoglio (1)

1 ICOA - Institut de Chimie Organique et Analytique

An efficient method for the synthesis of substituted ­furanopyrimidine nucleosides is described. Upon treatment with catalytic AgNO3, 5-alkynyl uracil derivatives were almost quanti­tatively converted into their corresponding bicyclic nucleoside ­analogues.

Domaines: Sciences du Vivant [q-bio]

Vincent Aucagne, Franck Amblard, Luigi Agrofoglio. Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].. ChemInform, 2005, 36 (18), ⟨10.1002/chin.200518181⟩. ⟨hal-02086027⟩