Comparative determination of placental perfusion by magnetic resonance imaging and contrast-enhanced ultrasound in a murine model of intrauterine growth restriction

Chloé Arthuis (1, 2) , V Mendes (2) , S. Même (3) , W. Même (3) , C. Rousselot , Norbert Winer (1) , A Novell (2) , Franck Perrotin (2)

1 PhAN - Physiopathologie des Adaptations Nutritionnelles
2 iBraiN - Imaging, Brain & Neuropsychiatry
3 CBM - Centre de biophysique moléculaire

Exploration of placental perfusion is essential in screening for dysfunctions impairing fetal growth. The objective of this study was to assess the potential value of contrast-enhanced ultrasonography (CEUS) and magnetic resonance imaging (MRI) for examining placental perfusion in a murine model of intrauterine growth restriction (IUGR). We also studied the reproducibility of perfusion quantification by CEUS.

Mots clés: CEUS; IUGR murine model; MRI; Placental perfusion

Domaines: Sciences du Vivant [q-bio]

Chloé Arthuis, V Mendes, S. Même, W. Même, C. Rousselot, et al.. Comparative determination of placental perfusion by magnetic resonance imaging and contrast-enhanced ultrasound in a murine model of intrauterine growth restriction. Placenta, 2018, 69, pp.74-81. ⟨10.1016/j.placenta.2018.07.009⟩. ⟨hal-02079394⟩