BLOCK DESIGNS FOR EARLY-STAGE CLINICAL TRIALS

Abstract : We provide a commented list of uniform on periods incomplete block designs appropriate for early-stage clinical trials. The optimality of these designs with respect to the NN1 and NN2 nearest-neighbour correlation models studied by Kiefer and Wynn (1981) and Morgan and Chakravarti (1988) is discussed.
Document type :
Preprints, Working Papers, ...
Complete list of metadatas

Cited literature [15 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-02068964
Contributor : Paul Deheuvels <>
Submitted on : Friday, March 15, 2019 - 1:22:05 PM
Last modification on : Wednesday, May 15, 2019 - 3:51:47 AM

File

Block Designs for Early Stage ...
Files produced by the author(s)

Identifiers

  • HAL Id : hal-02068964, version 1

Citation

Paul Deheuvels, Gérard Derzko. BLOCK DESIGNS FOR EARLY-STAGE CLINICAL TRIALS. 2019. ⟨hal-02068964⟩

Share

Metrics

Record views

29

Files downloads

30