Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A

Alexandre Erdmann , Yoann Menon (1) , Christina Gros (1) , Véronique Masson (2) , Yannick Aussagues , Frédéric Ausseil (1) , Natacha Novosad , Philippe Schambel , Michel Baltas (3) , Paola Arimondo (4)

1 ETaC - Pharmacochimie de la Régulation Epigénétique du Cancer
2 DREAM - Diagnosing, Recommending Actions and Modelling
3 SPCMIB - Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique
4 CNRS - Centre National de la Recherche Scientifique

Domaines: Chimie

Alexandre Erdmann, Yoann Menon, Christina Gros, Véronique Masson, Yannick Aussagues, et al.. Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A. Future Medicinal Chemistry, 2016, 8 (4), pp.373-380. ⟨10.4155/fmc.15.192⟩. ⟨hal-02060596⟩