Evolution of EBV seroprevalence and primary infection age in a French hospital and a city laboratory network, 2000–2016

Grégoire Fourcade , Raphaële Germi (1, 2) , Fabrice Guerber , Julien Lupo (1, 2) , Monique Baccard (3) , Arnaud Seigneurin (4) , Touyana Semenova , Patrice Morand (2) , Olivier Epaulard (2)

1 UGA UFRP - Université Grenoble Alpes - UFR Pharmacie
2 IBS - UMR 5075 - Institut de biologie structurale
3 Unit of virology
4 Service de Biostatistiques [Lyon]

According to rare studies, the age at EBV primary infection (PI) has recently risen in some developed countries. A later age at infection is generally considered a risk factor for severe EBV PI, although few studies exist on this subject. Our investigation aimed to determine whether EBV seroprevalence and EBV PI epidemiology have evolved in France, and to what extent age and infection intensity (regarding biological parameters) are correlated.

Domaines: Biologie structurale [q-bio.BM]

Grégoire Fourcade, Raphaële Germi, Fabrice Guerber, Julien Lupo, Monique Baccard, et al.. Evolution of EBV seroprevalence and primary infection age in a French hospital and a city laboratory network, 2000–2016. PLoS ONE, 2017, 12 (4), pp.e0175574. ⟨10.1371/journal.pone.0175574⟩. ⟨hal-02059906⟩