Tandem Rhodium Carbonylation Reactions

Philippe Kalck (1, 2) , Martine Urrutigoity (2, 1)

1 Toulouse INP - Institut National Polytechnique (Toulouse)
2 LCC - Laboratoire de chimie de coordination

This review presents the recent advances in the rhodium-catalyzed tandem carbonylation reactions involving in the main step the hydroformylation. Such reactions open huge opportunities in synthetic chemistry, since they offer a general efficient strategy to synthesize building blocks for fine chemistry, starting from abundant and low price substrates and avoiding the formation of substantial amounts of by-products. This atom-efficient tandem reaction approach shows that rhodium has a privileged place in the CO chemistry, not only to perform the hydroformylation reaction but also to functionalize the aldehyde function in a one-pot process.

Domaines: Chimie de coordination

Philippe Kalck, Martine Urrutigoity. Tandem Rhodium Carbonylation Reactions. Claver, C. Rhodium Catalysis, Springer, pp.1-30, 2018, Topics in Organometallic Chemistry, 978-3-319-66665-5. ⟨10.1007/3418_2016_170⟩. ⟨hal-02042491⟩