New unsaturated amino acids containing an allylsilane moiety on the lateral chain

Gianna Reginato (1, 2) , Alessandro Mordini (1, 2) , Patrick Meffre (3) , Alice Tenti (1, 2) , Michela Valacchi (1, 2) , Kevin Cariou (4)

1 ICCOM - Istituto di Chimica dei Composti Organometallici
2 UniFI - Università degli Studi di Firenze = University of Florence = Université de Florence
3 UNIMES - Centre universitaire de formation et de recherche de Nîmes (CUFR)
4 ICSN - Institut de Chimie des Substances Naturelles

New enantiomerically enriched polyfunctionalized allylsilanes have been obtained from the synthetic elaboration of naturally occurring serine. In particular, an oxazolidine bearing an allylsilane framework on the lateral chain proved to be a suitable precursor for the corresponding silylated vinyl glycine derivatives.

Domaines: Chimie organique

Gianna Reginato, Alessandro Mordini, Patrick Meffre, Alice Tenti, Michela Valacchi, et al.. New unsaturated amino acids containing an allylsilane moiety on the lateral chain. Tetrahedron: Asymmetry, 2006, 17 (6), pp.922-926. ⟨10.1016/j.tetasy.2006.02.017⟩. ⟨hal-02002619⟩