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Conference papers
Microfluidics and integrated optics glass sensor for in-line microprobing of nuclear samples
Abstract : We study the miniaturisation of Thermal Lens Spectrometry (TLS) towards Lab-on-chip integration in order to reduce the volume of fluid assays in nuclear process control. TLS is of great interest in this context since it combines the advantages of optical detection methods with an inherent suitability for small-scale samples. After validating the experimental principle in a classical thermal lens crossed-beam setup, we show the integration of a Young-interferometer with a microcapillary on a glass substrate, reducing the necessary sample size to 400 nl. The interferometer translates the photothermally induced refractive index change in the fluid to a phase shift of the fringe pattern, which can then be detected by a camera. Measurements of Co(II) in ethanol yield a detection limit of c = 5 ×10 -4 M for the crossed-beam setup and c = 6×10 -3 M for the integrated sensor. At an interaction length of 10μm, it detects a minimum absorbance of AU = 6 × 10 -5 in a probed volume of 10 pl.
https://hal.archives-ouvertes.fr/hal-01973040
Contributor : Davide Bucci <>
Submitted on : Tuesday, January 8, 2019 - 10:08:58 AM
Last modification on : Saturday, November 21, 2020 - 3:33:06 AM
Contributor : Davide Bucci <>
Submitted on : Tuesday, January 8, 2019 - 10:08:58 AM
Last modification on : Saturday, November 21, 2020 - 3:33:06 AM