An e-health interactive self-assessment website (Sanoia®) in rheumatoid arthritis. A 12-month randomized controlled trial in 320 patients

Laure Gossec (1, 2, 3) , Alain Cantagrel (4) , Martin Soubrier (5, 6) , Jean-Marie Berthelot (7) , Jean-Michel Joubert (8) , Bernard Combe (9, 10) , Wienia Czarlewski , Daniel Wendling (11) , Emmanuelle Dernis (12) , Laurent Grange , Catherine Beauvais (13) , Aleth Perdriger (14) , Henri Nataf (15) , Maxime Dougados (16, 17, 18) , Hervé Servy

1 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
2 CHU Pitié-Salpêtrière [AP-HP]
3 SU FM - Sorbonne Université - Faculté de Médecine
4 CHU Toulouse - Centre Hospitalier Universitaire de Toulouse
5 CHU Clermont-Ferrand
6 CHU Gabriel Montpied [Clermont-Ferrand]
7 Service de rhumatologie [Nantes]
8 UCB Laboratoire
9 Service d'immuno-rhumatologie[Montpellier]
10 CHU - Hôpital Lapeyronie [Montpellier]
11 CHRU Besançon - Centre Hospitalier Régional Universitaire de Besançon
12 Centre Hospitalier Le Mans (CH Le Mans)
13 CHU Saint-Antoine [AP-HP]
14 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
15 François Quesnay Hospital
16 Service de rhumatologie [CHU Cochin]
17 CRESS (U1153 / UMR_A_1125 / UMR_S_1153) - Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité
18 UPD5 - Université Paris Descartes - Paris 5

INTRODUCTION: Sanoia is an online interactive electronic e-health platform developed to allow patient self-assessment and self-monitoring. The objective was to assess in rheumatoid arthritis (RA) patients, the efficacy on patient-physician interactions, of giving access to Sanoia. METHODS: In this French, multi-center, 12-months randomized controlled trial (CarNET: NCT02200068), patients with RA and internet access were randomized to: access without incentives to the Sanoia platform after minimal training, or usual care. The primary outcome was the change from baseline in patient-physician interactions, by the patient-reported Perceived Efficacy in Patient-Physician Interactions (PEPPI-5) questionnaire. The number of accesses to Sanoia was recorded and satisfaction with the platform was assessed through a 0-10 numeric rating scale. Analyses were in intention to treat (ITT), on SAS. RESULTS: Of 320 RA patients (159 Sanoia versus 161 usual care), mean (standard deviation) age was 57.0 (12.7) years, mean (SD) disease duration was 14.6 (11.1) years, 216 (67.5%) were taking a biologic and 253 (79.1%) were female. Mean (SD) PEPPI scores at baseline and 12 months were 38.6 (8.2) and 39.2 (8.0) (delta=+0.60 [5.52]) versus 39.7 (7.3) and 38.8 (8.0) (delta=-0.91 [6.08]) in the Sanoia and control group, respectively (P=0.01). Although mean satisfaction with the platform was very high (1.46 [1.52]), 41 patients (25.7%) never accessed Sanoia. CONCLUSION: Giving RA patients access to the interactive Sanoia e-health platform led to a small improvement in patient-perceived patient-physician interactions. A disjunction between patient satisfaction and access to the platform was noted. E-Health platforms are promising in RA.

Mots clés: Patient-reported outcome measures; Quality of life; Rheumatoid arthritis; Patient attitude to health; Electronic health records; E-health; Disease activity; Quality of health care

Domaines: Rhumatologie et système ostéo-articulaire; Santé publique et épidémiologie

Laure Gossec, Alain Cantagrel, Martin Soubrier, Jean-Marie Berthelot, Jean-Michel Joubert, et al.. An e-health interactive self-assessment website (Sanoia®) in rheumatoid arthritis. A 12-month randomized controlled trial in 320 patients. Joint Bone Spine, 2018, 85 (6), pp.709-714. ⟨10.1016/j.jbspin.2017.11.015⟩. ⟨hal-01971775⟩