Repeated stimulation of dopamine D1-like receptor and hyperactivation of mTOR signaling lead to generalized seizures, altered dentate gyrus plasticity, and memory deficits

Giuseppe Gangarossa (1) , L. Ceolin , A. Paucard , Mireille Lerner-Natoli (1) , Julie Perroy (1) , Laurent Fagni (1) , Emmanuel Valjent (1)

1 IGF - Institut de Génomique Fonctionnelle

Mots clés: dopamine D1R; hippocampus; mTOR signaling; mem- ory; seizures

Domaines: Sciences du Vivant [q-bio]

Giuseppe Gangarossa, L. Ceolin, A. Paucard, Mireille Lerner-Natoli, Julie Perroy, et al.. Repeated stimulation of dopamine D1-like receptor and hyperactivation of mTOR signaling lead to generalized seizures, altered dentate gyrus plasticity, and memory deficits. Hippocampus, 2014, 24 (12), pp.1466--81. ⟨10.1002/hipo.22327⟩. ⟨hal-01944940⟩