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Poster De Conférence Année : 2018

Atmospheric Pressure Multijet Plasma Source for PlasmaMedicine Applications

Résumé

Single plasma jets have allowed significant advances in in vivo or directly on human experiments (e.g. [1], [2]). The results are particularly promising, but, ultimately, they couldbe limited in the future due to the fact that the treatment times are rather long due to the very small surface area treated by the produced plasma. There is a real challenge to develop sources that allow treatment over larger areas while remaining practical and at a reasonable cost. To this end, there are already flexible or rigid surface DBDs but they require an extremely small distance between the reactor and the treated tissues, which limits their use in many situations (particularly when the treated surfaces exhibit large variations in the surface morphology leading to points of attachment of streamers and therefore to a very inhomogeneous treatment). "Ideal" sources are therefore sources with the flexibility of a jet and treatment surfaces comparable to large DBDs. It is in this spirit that we have developed a new generation of applicators based on a single Plasma Gun system and able to generate a multitude of jets (from tens up to few hundreds) from theprimary plasma jet, as shown in Fig. 1. Fig. 1: Multijet plasma source from single Plasma Gun Before proceeding to in vivo treatments, we qualified the sourcesthrough in vitro experiments of decontamination on colonies grown on agar plates in traditional Petri dishes, to check the equivalence of each of the jets generated, as well as on colonies grown onvery large agarsurfaces scanned with our system,to check large surface treatment feasibility. The results are extremely encouraging and demonstrate the effectiveness of the multijet system, which allows both the processing of large-scale targets as well as the reductionof the processing times that otherwise can be prohibitive with single-jet systems.We will present experimental results obtained on the generation of different types of multijets, as well as results obtained with one multijet plasma source on the decontamination of multi-resistant bacterial colonies grown from hospital inpatient samples. Acknowledgements This work was supported by the CNRS PEPS project ACUMULTIPLAS and the ITMO Cancer in the frame of the Plan Cancer, project N°17CP086-00. References [1] L. Brulé et al, Plos One 7, 0052653 (2012) [2] H R Metelmannet al, CPM, 9, 6(2018)
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Dates et versions

hal-01943164 , version 1 (03-12-2018)

Identifiants

  • HAL Id : hal-01943164 , version 1

Citer

Thomas Maho, I Goard, Xavier Damany, Sébastien Dozias, Claire Douat, et al.. Atmospheric Pressure Multijet Plasma Source for PlasmaMedicine Applications. ICPM7, Jun 2018, Philadelphie, United States. ⟨hal-01943164⟩
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