Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies

R. Greget , Selma Dadak (1) , Laure Barbier (2) , Fabien Lauga (2) , Sandra Linossier-Pierre (2) , F. Pernot , A. Legendre , N. Ambert , J. M. Bouteiller , Frédéric Dorandeu (2) , S. Bischoff (3) , M. Baudry , Laurent Fagni (1) , S. Moussaoui

1 IGF - Institut de Génomique Fonctionnelle
2 IRBA - Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge]
3 Department of Nutritional Medicine/Prevention

Mots clés: Acetylcholine; Acetyl- and/or butyryl-cholinesterase; gamma-Aminobutyric acid; N-Methyl-d-aspartate; Organophosphorus; Paraoxon

Domaines: Sciences du Vivant [q-bio]

R. Greget, Selma Dadak, Laure Barbier, Fabien Lauga, Sandra Linossier-Pierre, et al.. Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies. NeuroToxicology, 2016, 54, pp.140--52. ⟨10.1016/j.neuro.2016.04.013⟩. ⟨hal-01941174⟩