High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast

Abstract : Low-grade adenosquamous carcinoma of the breast (LGASC) is a rare variant of metaplastic carcinoma characterised by a favourable outcome and histologically composed of glandular and squamous elements in a spindle cell background typically associated with a lymphocytic stromal reaction. Because of its rarity, the immunophenotypic and genetic profile of LGASC has not been sufficiently characterised. The aim of this study was to gain insights into the molecular and phenotypic characteristics of LGASC.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-01927072
Contributor : Mouniati Colo <>
Submitted on : Monday, November 19, 2018 - 3:53:28 PM
Last modification on : Friday, May 3, 2019 - 4:04:15 PM

Identifiers

Collections

Citation

Guillaume Bataillon, Laetitia Fuhrmann, Elodie Girard, Emanuelle Menet, Marick Laé, et al.. High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast. Histopathology, Wiley, 2018, 73 (2), pp.273 - 283. ⟨10.1111/his.13514⟩. ⟨hal-01927072⟩

Share

Metrics

Record views

32