Radiation dosimetry of [ 131 I]ICF01012 in rabbits: Application to targeted radionuclide therapy for human melanoma treatment

Abstract : Dosimetry for melanoma-targeted radionuclide therapy (TRT) with [131 I]ICF01012, a melanin ligand, has been previously evaluated in mice bearing melanomas. In this study, activity distribution and dosimetry are performed on healthy rabbits (Fauve de Bourgogne) using SPECT-CT imaging and ex vivo measurements.
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https://hal.archives-ouvertes.fr/hal-01925049
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Submitted on : Friday, November 16, 2018 - 2:24:39 PM
Last modification on : Tuesday, April 23, 2019 - 12:41:53 PM

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Elodie Jouberton, Yann Perrot, Béatrice Dirat, Tommy Billoux, Philippe Auzeloux, et al.. Radiation dosimetry of [ 131 I]ICF01012 in rabbits: Application to targeted radionuclide therapy for human melanoma treatment. Medical Physics, American Association of Physicists in Medicine, 2018, 45 (11), pp.5251 - 5262. ⟨10.1002/mp.13165⟩. ⟨hal-01925049⟩

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