New directions in membrane designs for biosensors

Ilanna Campelo Lopes (1) , Abdelkader Zebda (2) , Pankaj Vadgama (1)

1 QMUL - Queen Mary University of London
2 TIMC-IMAG-SyNaBi - Systèmes Nanobiotechnologiques et Biomimétiques

For practical outcomes, to avoid cumbersome and undesirable sample preparation, biosensors require engineered sample interfacing to control the dynamics of exchange at the sensing surface. This is a particular priority for biomedical biosensors, given the diversity of cellular and macromolecular sample constituents capable of disrupting not only the transduction sequence, but also of passivating the vulnerable sensing surface. Polymeric, and to a lesser extent inorganic membranes offer the most effective of the available technologies for this. This review covers the most recent work in this area, and through this provides indication of new directions and the consolidation of existing ones. The growing need to deliver advanced materials solutions for operational biosensors is likely to accelerate future development in this adjunct area.

Domaines: Chimie; Sciences du Vivant [q-bio]; Biotechnologies

Ilanna Campelo Lopes, Abdelkader Zebda, Pankaj Vadgama. New directions in membrane designs for biosensors. Current Opinion in Electrochemistry, 2018, 12, pp.107-112. ⟨10.1016/j.coelec.2018.07.009⟩. ⟨hal-01922039⟩