High frequency percussive ventilation increases alveolar recruitment in early acute respiratory distress syndrome: an experimental, physiological and CT scan study

Thomas Godet (1) , Matthieu Jabaudon (2) , Raiko Blondonnet (3) , Aymeric Tremblay , Jules Audard , Benjamin Rieu , Bruno Pereira (2) , Jean-Marc Garcier (4) , Emmanuel Futier (5) , Jean-Michel Constantin (2)

1 ICBMS - Institut de Chimie et Biochimie Moléculaires et Supramoléculaires
2 CHU Clermont-Ferrand
3 R2D2 - Retinoids, Development and Developmental Diseases
4 IP - Institut Pascal
5 GReD - Génétique, Reproduction et Développement

Background: High frequency percussive ventilation (HFPV) combines diffusive (high frequency mini-bursts) and convective ventilation patterns. Benefits include enhanced oxygenation and hemodynamics, and alveolar recruitment, while providing hypothetic lung-protective ventilation. No study has investigated HFPV-induced changes in lung aeration in patients with early acute respiratory distress syndrome (ARDS).

Domaines: Pneumologie et système respiratoire; Physiologie [q-bio.TO]

Thomas Godet, Matthieu Jabaudon, Raiko Blondonnet, Aymeric Tremblay, Jules Audard, et al.. High frequency percussive ventilation increases alveolar recruitment in early acute respiratory distress syndrome: an experimental, physiological and CT scan study. Critical Care, 2018, 22 (1), ⟨10.1186/s13054-017-1924-6⟩. ⟨hal-01919300⟩