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Article Dans Une Revue Science of the Total Environment Année : 2018

Immune failure reveals vulnerability of populations exposed to pollution in the bioindicator species Hediste diversicolor

Résumé

Human activities on the shoreline generate a growing pollution, creating deleterious habitats in coastal zones. Some species nevertheless succeed in such harsh milieus, raising the question of their tolerance to environmental stress. The annelid Hediste diversicolor lives buried in the sediments, directly exposed to contaminants trapped in the mud. After verifying the similarity of their genetic contexts, we compared reproductive output and individual immune resistance measures of populations living in polluted vs. ‘clean’ sediments, and related these assessments with measures of phthalates and metal pollution, and associated toxicity indices. Chemical analyses predicted no toxicity to the local infauna, and phenological studies evidenced no direct cost of living in noxious habitats. However, populations exposed to pollutants showed a significantly reduced survival upon infection with a local pathogen. Surprisingly, physiological studies evidenced a basal overinflammatory state in the most exposed populations. This over-activated baseline immune phenotype likely generates self-damage leading to enhanced immune cell death rate and immune failure. Monitoring the immune status of individual worms living in anthropic areas could thus be used as a reliable source of information regarding the actual health of wild populations.
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Dates et versions

hal-01597852 , version 1 (28-09-2017)

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Virginie Cuvillier-Hot, Sylvie Marylène Gaudron, Francois Massol, Céline Boidin-Wichlacz, Timothée Pennel, et al.. Immune failure reveals vulnerability of populations exposed to pollution in the bioindicator species Hediste diversicolor. Science of the Total Environment, 2018, 613-614, pp.1527-1542. ⟨10.1016/j.scitotenv.2017.08.259⟩. ⟨hal-01597852⟩
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