Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures

Adeline Tarantini (1, 2) , Anne Maitre (3, 4) , Emmanuel Lefebvre , Marie Marques (4) , Caroline Marie (5) , Jean-Luc Ravanat (1) , Thierry Douki (1)

1 LAN - Laboratoire Lésions des Acides Nucléiques
2 EPSP
3 CHUGA - Centre Hospitalier Universitaire [CHU Grenoble]
4 EPSP
5 EPSP

Domaines: Toxicologie; Biologie cellulaire; Cancer; Sciences du Vivant [q-bio]

Adeline Tarantini, Anne Maitre, Emmanuel Lefebvre, Marie Marques, Caroline Marie, et al.. Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2009, 671 (1-2), pp.67 - 75. ⟨10.1016/j.mrfmmm.2009.08.014⟩. ⟨hal-01903200⟩