Validation of cadmium–zinc–telluride camera for measurement of left ventricular systolic performance

Abstract : BACKGROUND: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging. METHODS: 60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement. RESULTS: 48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques. CONCLUSIONS: CZT-SPECT is reliable for LVEF measurement.
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Submitted on : Thursday, October 4, 2018 - 3:26:33 PM
Last modification on : Friday, March 1, 2019 - 10:48:31 AM

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Elisabeth Coupez, Charles Merlin, Viateur Tuyisenge, Laurent Sarry, Bruno Pereira, et al.. Validation of cadmium–zinc–telluride camera for measurement of left ventricular systolic performance. Journal of Nuclear Cardiology, Springer Verlag, 2018, 25 (3), pp.1029 - 1036. ⟨10.1007/s12350-017-0816-0⟩. ⟨hal-01887852⟩

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