A. Alam, R. C. Larocque, J. B. Harris, C. Vanderspurt, E. T. Ryan et al., Hyperinfectivity of human-passaged Vibrio cholerae can be modeled by growth in the infant mouse, Infect Immun, vol.73, pp.6674-6679, 2005.

A. Azandegbe, M. Garnier, F. Andrieux-loyer, R. Kerouel, X. Philippon et al., Occurrence and seasonality of Vibrio aestuarianus in sediment and Crassostrea gigas haemolymph at two oyster farms in France, Diseases of Aquatic Organisms, vol.91, pp.213-221, 2010.

V. Barbosa-solomieu, T. Renault, T. , and M. A. , Mass mortality in bivalves and the intricate case of the Pacific oyster, Crassostrea gigas, J Invertebr Pathol, vol.131, pp.2-10, 2015.

M. Bruto, A. James, B. Petton, Y. Labreuche, S. Chenivesse et al., Vibrio crassostreae, a benign oyster colonizer turned into a pathogen after plasmid acquisition, ISME J, vol.11, pp.1043-1052, 2017.
DOI : 10.1038/ismej.2016.162
URL : https://hal.archives-ouvertes.fr/hal-01483219

S. M. Butler, E. J. Nelson, N. Chowdhury, S. M. Faruque, S. B. Calderwood et al., Cholera stool bacteria repress chemotaxis to increase infectivity, Mol Microbiol, vol.60, pp.417-426, 2006.
DOI : 10.1111/j.1365-2958.2006.05096.x
URL : https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2958.2006.05096.x

M. L. Chaney and A. Y. Gracey, Mass mortality in Pacific oysters is associated with a specific gene expression signature, Mol Ecol, vol.20, pp.2942-2954, 2011.

J. Couch, Atrophy of diverticular epithelium as an indicator of environmental irritants in the oyster Crassostrea virginica, Mar Environ Res, vol.14, pp.525-526, 1984.

A. Depaola, J. L. Nordstrom, J. C. Bowers, J. G. Wells, and D. W. Cook, Seasonal abundance of total and pathogenic Vibrio parahaemolyticus in Alabama oysters, Appl Environ Microbiol, vol.69, pp.1521-1526, 2003.

M. Duperthuy, P. Schmitt, E. Garzon, A. Caro, R. D. Rosa et al., Use of OmpU porins for attachment and invasion of Crassostrea gigas immune cells by the oyster pathogen Vibrio splendidus, Proceedings of the National Academy of Sciences of the United States of America, vol.108, pp.2993-2998, 2011.

B. Froelich, M. Ayrapetyan, and J. D. Oliver, Integration of Vibrio vulnificus into Marine Aggregates and Its Subsequent Uptake by Crassostrea virginica Oysters, Applied and environmental microbiology, vol.79, pp.1454-1458, 2013.
DOI : 10.1128/aem.03095-12
URL : https://aem.asm.org/content/79/5/1454.full.pdf

M. Garnier, Y. Labreuche, C. Garcia, M. Robert, N. et al., Evidence for the involvement of pathogenic bacteria in summer mortalities of the Pacific oyster Crassostrea gigas, Microb Ecol, vol.53, pp.187-196, 2007.

D. Goudenege, M. A. Travers, A. Lemire, B. Petton, P. Haffner et al., A single regulatory gene is sufficient to alter Vibrio aestuarianus pathogenicity in oysters, Environ Microbiol, vol.17, pp.4189-4199, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01444897

M. A. Hayat, Stains and cytochemical methods, pp.63-64, 1993.

D. E. Hunt, L. A. David, D. Gevers, S. P. Preheim, E. J. Alm et al., Resource partitioning and sympatric differentiation among closely related bacterioplankton, Science, vol.320, pp.1081-1085, 2008.
DOI : 10.1126/science.1157890

G. Knowles, J. Handlinger, B. Jones, and N. Moltschaniwskyj, Hemolymph chemistry and histopathological changes in Pacific oysters (Crassostrea gigas) in response to low salinity stress, J Invertebr Pathol, vol.121, pp.78-84, 2014.
DOI : 10.1016/j.jip.2014.06.013

Y. Labreuche, P. Soudant, M. Goncalves, C. Lambert, N. et al., Effects of extracellular products from the pathogenic Vibrio aestuarianus strain 01/32 on lethality and cellular immune responses of the oyster Crassostrea gigas, Dev Comp Immunol, vol.30, pp.367-379, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00629874

Y. Labreuche, C. Lambert, P. Soudant, V. Boulo, A. Huvet et al., Cellular and molecular hemocyte responses of the Pacific oyster, Crassostrea gigas, following bacterial infection with Vibrio aestuarianus strain 01/32, Microbes and Infection, vol.8, pp.2715-2724, 2006.
DOI : 10.1016/j.micinf.2006.07.020
URL : https://hal.archives-ouvertes.fr/hal-00670385

Y. Labreuche, F. Le-roux, J. Henry, C. Zatylny, A. Huvet et al., Vibrio aestuarianus zinc metalloprotease causes lethality in the Pacific oyster Crassostrea gigas and impairs the host cellular immune defenses, Fish & shellfish immunology, vol.29, pp.753-758, 2010.
DOI : 10.1016/j.fsi.2010.07.007
URL : https://hal.archives-ouvertes.fr/hal-00670371

F. Le-roux, K. M. Wegner, and M. F. Polz, Oysters and Vibrios as a Model for Disease Dynamics in Wild Animals, Trends Microbiol, vol.24, pp.568-580, 2016.

A. Lemire, D. Goudenege, T. Versigny, B. Petton, A. Calteau et al., Populations, not clones, are the unit of vibrio pathogenesis in naturally infected oysters, ISME J, 2014.

D. H. Lenz, M. B. Miller, J. Zhu, R. V. Kulkarni, and B. L. Bassler, CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae, Mol Microbiol, vol.58, pp.1186-1202, 2005.
DOI : 10.1111/j.1365-2958.2005.04902.x
URL : https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2958.2005.04902.x

A. Marques, F. Ollevier, W. Verstraete, P. Sorgeloos, and P. Bossier, Gnotobiotically grown aquatic animals: opportunities to investigate host-microbe interactions, J Appl Microbiol, vol.100, pp.903-918, 2006.

C. Martenot, E. Oden, E. Travaille, J. P. Malas, and M. Houssin, Detection of different variants of Ostreid Herpesvirus 1 in the Pacific oyster, Crassostrea gigas between, vol.160, pp.25-31, 2008.

C. Martenot, E. Travaille, O. Lethuillier, C. Lelong, and M. Houssin, Genome exploration of six variants of the Ostreid Herpesvirus 1 and characterization of large deletion in OsHV-1muVar specimens, Virus Res, vol.178, pp.462-470, 2013.

C. Martenot, A. Segarra, L. Baillon, N. Faury, M. Houssin et al., In situ localization and tissue distribution of ostreid herpesvirus 1 proteins in infected Pacific oyster, Crassostrea gigas, J Invertebr Pathol, vol.136, pp.124-135, 2016.

R. Martoja and M. Martoja, Initiation aux techniques de l'histologie animale, Masson et Cie, Editeurs, vol.120, 1967.

D. S. Merrell, D. L. Hava, C. , and A. , Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae, Mol Microbiol, vol.43, pp.1471-1491, 2002.

J. A. Olafsen, H. V. Mikkelsen, H. M. Giaever, H. Hansen, and G. , Indigenous bacteria in hemolymph and tissues of marine bivalves at low temperatures, Appl Environ Microbiol, vol.59, pp.1848-1854, 1993.

J. F. Pepin, A. Riou, R. , and T. , Rapid and sensitive detection of ostreid herpesvirus 1 in oyster samples by real-time PCR, Journal of Virological Methods, vol.149, pp.269-276, 2008.

B. Petton, M. Bruto, A. James, Y. Labreuche, M. Alunno-bruscia et al., Crassostrea gigas mortality in France: the usual suspect, a herpes virus, may not be the killer in this polymicrobial opportunistic disease, Frontiers in Microbiology, vol.6, p.686, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01216445

E. Pezzati, L. Canesi, G. Damonte, A. Salis, F. Marsano et al., Susceptibility of Vibrio aestuarianus 01/032 to the antibacterial activity of Mytilus haemolymph: identification of a serum opsonin involved in mannose-sensitive interactions, Environmental Microbiology, vol.17, pp.4271-4279, 2015.

D. Saulnier, S. De-decker, and P. Haffner, Real-time PCR assay for rapid detection and quantification of Vibrio aestuarianus in oyster and seawater: A useful tool for epidemiologic studies, Journal of Microbiological Methods, vol.77, pp.191-197, 2009.

D. Schikorski, N. Faury, J. F. Pepin, D. Saulnier, D. Tourbiez et al., Experimental ostreid herpesvirus 1 infection of the Pacific oyster Crassostrea gigas: kinetics of virus DNA detection by q-PCR in seawater and in oyster samples, Virus research, vol.155, pp.28-34, 2011.

D. Schikorski, T. Renault, D. Saulnier, N. Faury, P. Moreau et al., Experimental infection of Pacific oyster Crassostrea gigas spat by ostreid herpesvirus 1: demonstration of oyster spat susceptibility, Veterinary research, vol.42, p.27, 2011.

S. Schild, R. Tamayo, E. J. Nelson, F. Qadri, S. B. Calderwood et al., Genes induced late in infection increase fitness of Vibrio cholerae after release into the environment, Cell Host Microbe, vol.2, pp.264-277, 2007.

P. Schmitt, Y. Gueguen, E. Desmarais, E. Bachere, and J. De-lorgeril, Molecular diversity of antimicrobial effectors in the oyster Crassostrea gigas, Bmc Evolutionary Biology, vol.10, 2010.

A. Segarra, J. F. Pepin, I. Arzul, B. Morga, N. Faury et al., Detection and description of a particular Ostreid herpesvirus 1 genotype associated with massive mortality outbreaks of Pacific oysters, Crassostrea gigas, Virus Research, vol.153, pp.92-99, 2008.

A. Segarra, F. Mauduit, N. Faury, S. Trancart, L. Degremont et al., Dual transcriptomics of virus-host interactions: comparing two Pacific oyster families presenting contrasted susceptibility to ostreid herpesvirus 1, BMC Genomics, vol.15, p.580, 2014.

J. R. Thompson, M. A. Randa, L. A. Marcelino, A. Tomita-mitchell, E. Lim et al., Diversity and Dynamics of a North Atlantic Coastal Vibrio Community, Applied and Environmental Microbiology, vol.70, pp.4103-4110, 2004.

M. A. Travers, K. Boettcher-miller, A. Roque, and C. S. Friedman, Bacterial diseases in marine bivalves, J Invertebr Pathol, vol.131, pp.11-31, 2015.

A. S. Vanhove, T. P. Rubio, A. N. Nguyen, A. Lemire, D. Roche et al., Copper homeostasis at the host vibrio interface: lessons from intracellular vibrio transcriptomics, Environ Microbiol, vol.18, pp.875-888, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01311061

L. Vezzulli, E. Pezzati, M. Stauder, L. Stagnaro, P. Venier et al., Aquatic ecology of the oyster pathogens Vibrio splendidus and Vibrio aestuarianus, Environ Microbiol, vol.17, pp.1065-1080, 2015.