Single substitution in bacteriophage T4 RNase H alters the ratio between its exo- and endonuclease activities

Natalia Kholod (1) , Dmitry Sivogrivov (1) , Oleg Latypov (1) , Sergey Mayorov (1) , Rafail Kuznitsyn (1) , Andrey V. Kajava (2, 3) , Mikhail Shlyapnikov (1) , Igor Granovsky (1)

1 Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow region
2 CRBM - Centre de recherche en Biologie cellulaire de Montpellier
3 ITMO - National Research University of Information Technologies, Mechanics and Optics [St. Petersburg]

Domaines: Biologie cellulaire; Biophysique

Natalia Kholod, Dmitry Sivogrivov, Oleg Latypov, Sergey Mayorov, Rafail Kuznitsyn, et al.. Single substitution in bacteriophage T4 RNase H alters the ratio between its exo- and endonuclease activities. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2015, 781, pp.49--57. ⟨10.1016/j.mrfmmm.2015.09.004⟩. ⟨hal-01883497⟩