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Journal articles
Effect of a Glyphosate-Based Herbicide on Gene Expressions of the Cytokines Interleukin-1β and Interleukin-10 and of Heme Oxygenase-1 in European Sea Bass, Dicentrarchus labrax L.
Abstract : Glyphosate-based herbicides are the most frequently used herbicides in the world. We evaluated the effect of Roundup 360 SL on the expression of interleukin-1β (il-1β), interleukin-10 (il-10) and heme-oxygenase-1 (ho-1) in the gills, intestines and spleen of young European sea bass (Dicentrachus labrax L.), aged 8 mo. A group of fish was exposed to 647 mg/L of Roundup for 96 h. This treatment did not alter gene expression levels of il-1β and il-10 cytokine in the intestines, but significantly lowered both levels in the gills (p = 0.02 and p = 0.04 respectively). Expression levels of ho-1 were increased significantly in the three organs of fish from the treated group (the gills p = 0.04, the intestines p = 0.004 and the spleen p < 0.001). These changes may in turn negatively impact the immune system of European sea bass exposed to Roundup.
https://hal.archives-ouvertes.fr/hal-01883026
Contributor : Simone Richard <>
Submitted on : Thursday, September 27, 2018 - 3:57:56 PM
Last modification on : Tuesday, September 24, 2019 - 2:02:06 PM
Contributor : Simone Richard <>
Submitted on : Thursday, September 27, 2018 - 3:57:56 PM
Last modification on : Tuesday, September 24, 2019 - 2:02:06 PM